Medicated shampoo helps control seborrheic dermatitis on the scalp. It reduces flakes, itching, redness, and greasy scales. These shampoos work by fighting fungus, lowering oil, and slowing skin buildup.
Common active ingredients include ketoconazole, zinc pyrithione, selenium sulfide, coal tar, and salicylic acid. Medicated shampoo is usually used two or three times a week, not every day.
| Shampoo Name | Active Ingredient(s) | What It’s Best For | Key Notes |
|---|---|---|---|
| Nizoral Anti-Dandruff Shampoo | Ketoconazole | Strong antifungal action | Good for moderate–severe cases; fights fungus directly |
| Selsun Blue Medicated Maximum Strength Shampoo | Selenium Sulfide | Reducing fungus and itch | Strong formula; cooling feel; may feel heavy |
| Neutrogena T/Gel Therapeutic Shampoo | Coal Tar | Slowing skin cell growth | Helps with thick flakes and irritation; strong smell |
| Head & Shoulders Clinical Strength Shampoo | Selenium Sulfide / Zinc Pyrithione | Controlling yeast and flakes | Accessible; often gentler than stronger medicated shampoos |
| Neutrogena T/Sal Therapeutic Shampoo | Salicylic Acid | Removing dead skin and buildup | Great for heavy scaling; doesn’t kill fungus directly |
| DHS Zinc Shampoo | Zinc Pyrithione | Reducing fungus and irritation | Good for sensitive scalps; gentle antifungal |
| BIOLAGE Scalpsync Anti-Dandruff Shampoo | Pyrithione Zinc | Antifungal + smoother feel | Cooling & comfortable; good for mild–moderate symptoms |
| TELOGEFF SD Seborrheic Dermatitis Treatment Shampoo | Climbazole + Zinc Pyrithione + Salicylic Acid | Multi-action (fungus + build-up) | Targets flakes, fungus, and hair support |
| Nioxin Scalp Recovery Medicated Cleanser Shampoo | Pyrithione Zinc + Botanical extracts | Soothing and antifungal | Calms irritation; good for sensitive or reactive scalps |
| DHS Sal Shampoo | Salicylic Acid | Heavy scale removal | Good for stubborn flakes; not antifungal on its own |
1. Nizoral Anti-Dandruff Shampoo (Ketoconazole Shampoo)
What it is:
Nizoral is a medicated shampoo with ketoconazole, a strong antifungal ingredient. This means it helps control the fungus (Malassezia) that can make seborrheic dermatitis worse. It is one of the most recommended shampoos when flakes are thick, itchy, and stubborn.
What it does:
When you wash your hair with Nizoral, ketoconazole works by limiting the fungus growth on your scalp. Seborrheic dermatitis is often linked to this fungus, so reducing it can calm itchiness, reduce oiliness, and make flakes less visible. Many people report that they see a difference after a few uses, especially if they use it as directed (for example, 2–3 times per week).
How to use it:
Apply the shampoo to wet hair and scalp, massage gently, and let it sit for a few minutes before rinsing. You don’t need to wash your whole hair each day with it — often just the scalp is enough. The goal is to get the active ingredient onto the skin where symptoms show up. Over time, users often switch between medicated and gentle cleansing shampoos to keep the scalp calm.
Pros:
- Targets fungus directly.
- Often works when other shampoos don’t.
- Can reduce itching and flaking noticeably.
Cons:
- Some people find it feels strong or drying if used every day.
- You need to follow directions to avoid irritation.
Summary:
Nizoral is a strong choice if typical dandruff shampoos are not enough. It works by fighting fungus and easing symptoms like itching and flakes. It’s a good option if you have moderate to severe seborrheic dermatitis and need targeted antifungal action.
2. Selsun Blue Medicated Maximum Strength Shampoo (Selenium Sulfide)
What it is:
Selsun Blue Medicated is a medicated shampoo with selenium sulfide — a powerful ingredient that fights the fungus associated with dandruff and seborrheic dermatitis. It also helps slow down skin cell turnover on the scalp, which reduces flaking.
What it does:
When you use Selsun Blue Medicated, the selenium sulfide goes to work on the surface of the scalp. It helps reduce oiliness and yeast growth that can feed seborrheic dermatitis. Many people find that their scalp feels less itchy and flakey after a few washes.
This shampoo often comes with a gentle cooling feeling which can help calm scalp discomfort. It might make hair feel heavier or slightly oily sometimes because of its strong formula, but that is normal for medicated products.
How to use it:
Wet your hair and massage the shampoo into your scalp. Leave it on for a couple of minutes before rinsing well. You might use it only on the scalp area, not all the way to the ends of your hair, depending on how strong the formula feels for you.
Pros:
- Strong antifungal action.
- Helps reduce itch and flakes.
- Cooling sensation for comfort.
Cons:
- Hair may feel oily or heavier.
- Some people say the scent is strong.
Summary:
Selsun Blue Medicated is a reliable choice when you want a strong medicated shampoo for seborrheic dermatitis. Its active ingredient works against the root problems of flaking and itch, helping to make your scalp calmer over time.
3. Neutrogena T/Gel Therapeutic Shampoo (Coal Tar Shampoo)
What it is:
Neutrogena T/Gel Therapeutic Shampoo contains coal tar extract, an ingredient that helps slow the rapid growth of skin cells on the scalp. Too much cell turnover can make flakes and irritation worse.
What it does:
Coal tar works by calming inflammation and reducing how fast dead skin cells pile up on the scalp surface. For seborrheic dermatitis, where flakes and itch can come from fast skin cell growth and oiliness, this helps ease visible symptoms. Many people with chronic scalp problems (like tough dandruff or psoriasis) use T/Gel because it gives real relief for scaling and irritation.
Like other medicated shampoos, it should be used as part of a care routine — not necessarily every day, unless advised by a doctor.
How to use it:
Apply it to wet hair and massage across the scalp. Let it sit for a few minutes so the active ingredient can begin working, then rinse well. Some users follow with a gentle conditioner to avoid dryness.
Pros:
- Helps reduce scaling and visible buildup.
- Soothes inflammation.
Cons:
- Coal tar has a strong smell.
- Some people find it feels heavy on the hair.
Summary:
Neutrogena T/Gel is good if your seborrheic dermatitis also comes with thick flakes or irritation that doesn’t respond to gentler shampoos. Its coal tar formula slows cell turnover and helps calm visible signs over time.
4. Head & Shoulders Clinical Strength Shampoo (Selenium Sulfide or Zinc Pyrithione)
What it is:
Head & Shoulders is a well-known medicated shampoo brand. The Clinical Strength version usually has strong antifungal ingredients like selenium sulfide or zinc pyrithione. These help control the yeast that can lead to seborrheic dermatitis flaking and itching.
What it does:
This shampoo works by reducing yeast on the scalp and slowing down excess skin cell production. By doing this, it can lower scalp irritation and help make flakes less visible. Many people use it a few times per week and find that their scalp stays calmer between washes. It’s often gentler than some prescription products but still effective for many cases.
How to use it:
Massage into a wet scalp, leave for 1–3 minutes, and then rinse well. Some people focus just on the scalp instead of the whole hair length. Using it consistently helps keep symptoms down.
Pros:
- Well tolerated by many skin types.
- Helps with itch and flake control.
- Often more affordable.
Cons:
- May not be strong enough for severe cases.
- A scent may be noticeable.
Summary:
Head & Shoulders Clinical Strength is a good medicated option for seborrheic dermatitis that is easier to find in many stores. Its antifungal actions help reduce symptoms and make scalp care more manageable.
5. Neutrogena T/Sal Therapeutic Shampoo (Salicylic Acid Shampoo)
What it is:
Neutrogena T/Sal contains salicylic acid, which helps remove dead skin cells and buildup on the scalp. This ingredient works by gently breaking down the outer layer of skin so flakes and scales come off more easily.
What it does:
For seborrheic dermatitis, the problem often includes thick, stuck-on flakes. Salicylic acid helps loosen these flakes so they rinse away instead of clinging to hair and scalp. This doesn’t directly kill fungus like other medicated shampoos, but it makes the scalp feel cleaner and less itchy.
This shampoo is often recommended when dead skin buildup is heavy and other shampoos don’t remove flakes well.
How to use it:
Wet your hair and massage the shampoo onto the scalp. Give it a few minutes to work, then rinse thoroughly. Some people follow with a gentle conditioner to avoid dryness, as salicylic acid can feel drying if overused.
Pros:
- Helps lift thick flakes.
- Easy to use with other medicated shampoos.
Cons:
- Not antifungal on its own.
- Can dry hair if used too often.
Summary:
Neutrogena T/Sal is a great choice if you struggle with heavy buildup and scaling. It works by loosening dead skin so it can be rinsed away, making your scalp feel clearer and more comfortable.
6. DHS Zinc Shampoo (Zinc Pyrithione Shampoo)
What it is:
DHS Zinc Shampoo contains zinc pyrithione, which helps reduce the fungus and bacteria that can contribute to dandruff and seborrheic dermatitis. It’s a medicated shampoo that aims to calm both itching and flaking.
What it does:
This shampoo fights the microscopic organisms that feed on oil on the scalp. When those organisms grow too much, they can trigger redness, itch, and flaky skin. DHS Zinc Shampoo lowers their numbers and helps your scalp feel less irritated. It’s often free from strong fragrances and other harsh chemicals, which can make it a good option for sensitive skin.
How to use it:
Massage into wet scalp and let it sit for a few minutes before rinsing. Using it regularly (a few times a week) helps keep the scalp balanced.
Pros:
- Good for sensitive scalps.
- Helps control fungus and irritation.
Cons:
- Might be not as strong for severe cases.
- Can leave a slight residue if not rinsed well.
Summary:
DHS Zinc Shampoo is a solid medicated choice for seborrheic dermatitis, especially if your scalp is sensitive or reacts to stronger shampoos. Its zinc pyrithione works gently to reduce flakes and itch.
7. BIOLAGE Scalpsync Anti-Dandruff Shampoo (Pyrithione Zinc Shampoo)
What it is:
BIOLAGE Scalpsync is a salon-quality shampoo that uses pyrithione zinc to help fight the fungus that contributes to dandruff and seborrheic dermatitis. It combines medicated action with a smooth cleansing experience.
What it does:
When you use this shampoo, the zinc helps reduce the yeast on your scalp that can cause flakes and itch. The formula also includes ingredients that leave the hair feeling softer and easier to manage, which can be nice for people who find medicated shampoos harsh.
This shampoo also has a cooling effect that many users enjoy. Even though it’s medicated, it feels more luxurious than some plain drugstore formulas, which makes it a good everyday choice for mild to moderate symptoms.
How to use it:
Apply to wet hair, especially massaging the scalp, and leave it on for a couple of minutes before rinsing. Consistent use helps maintain a calmer scalp.
Pros:
- Gentle yet effective.
- Good for regular use.
- Cooling sensation.
Cons:
- Might be less strong for severe flaking.
- Usually more expensive than simple drugstore shampoos.
Summary:
BIOLAGE Scalpsync is a medicated shampoo that blends antifungal activity with a pleasant wash experience. It’s ideal if you want treatment and comfort together.
8. TELOGEFF SD Seborrheic Dermatitis Treatment Shampoo
What it is:
TELOGEFF SD is a specialized medicated shampoo made to treat seborrheic dermatitis directly. It combines antifungal ingredients like climbazole and zinc pyrithione with salicylic acid to exfoliate dead skin and reduce flakes.
What it does:
This unique mix helps in three ways:
- Antifungal: Climbazole and zinc pyrithione help reduce fungus and microbes that trigger irritation.
- Exfoliating: Salicylic acid gently dissolves buildup.
- Hair support: Added biotin and panthenol support hair strength and may reduce hair loss related to scratching.
People who use this shampoo say it targets both symptoms (like itch and flakes) and the underlying buildup that makes the scalp look bad. Some formulas are designed for long-term use, but you should still follow instructions to avoid dryness.
How to use it:
Massage into the scalp on wet hair. Let it sit for a few minutes, then rinse. You might follow it with a conditioner on the hair lengths to keep them soft.
Pros:
- Multi-action formula.
- Helps with flakes and hair strength.
- Targets dandruff and dermatitis at multiple points.
Cons:
- Some people may find it strong at first.
- Fragrance in some versions can irritate sensitive scalps.
Summary:
TELOGEFF SD is a good medicated shampoo if you want a formula that fights fungus, unclogs dead skin, and supports hair health at the same time.
9. Nioxin Scalp Recovery Medicated Cleanser Shampoo
What it is:
Nioxin Scalp Recovery Medicated Cleanser is a scalp-focused shampoo that uses pyrithione zinc and soothing botanical extracts to help calm seborrheic dermatitis symptoms.
What it does:
This medicated cleanser reduces fungus that causes flakes and irritation. It also includes plant extracts (like green tea) and minerals to soothe redness, calm itchiness, and help your scalp feel more balanced. Some people prefer this shampoo because it doesn’t feel as harsh as stronger antifungal shampoos, yet still delivers relief.
Its formula aims to exfoliate lightly while calming inflammation, making it a good choice when your scalp feels sensitive and reactive.
How to use it:
Massage the shampoo into the wet scalp, focusing on itchy or flaky areas, and leave it for a few minutes before rinsing. Many users alternate this with a gentler shampoo to avoid dryness.
Pros:
- Soothing and calming.
- Good for sensitive scalps.
- Helps reduce visible flakes.
Cons:
- May be less strong for severe dermatitis.
- Pricier than basic medicated shampoos.
Summary:
Nioxin Scalp Recovery Medicated Cleanser is a nice balance of medicated action and scalp-soothing comfort. It helps reduce flakes while calming itch and irritation.
10. DHS Sal Shampoo (Salicylic Acid Shampoo)
What it is:
DHS Sal Shampoo contains salicylic acid, a keratolytic agent that helps break up dead skin and scales on the scalp. It’s a simple yet effective medicated shampoo that many dermatologists recommend when flakes are thick.
What it does:
The salicylic acid works on the outer layer of skin. When dead skin builds up and sticks to the scalp, it causes visible flakes and can trap oil and fungus. Salicylic acid helps loosen that buildup so it can be rinsed away, leaving the scalp feeling cleaner and less itchy. This doesn’t kill fungus directly, but by clearing buildup it helps reduce the environment where fungus grows.
People often use DHS Sal Shampoo when flakes are large, thick, or stubborn. It can feel a bit drying, so many users pair it with a gentle conditioner after washing.
How to use it:
Massage into wet hair and let it stay for a few minutes, then rinse thoroughly. You can use it a few times per week as part of a routine.
Pros:
- Helps remove heavy buildup.
- Simple formula.
- Good for stubborn flakes.
Cons:
- Not antifungal on its own.
- Can dry hair if used too often.
Summary:
DHS Sal Shampoo is a reliable medicated shampoo when dead skin buildup is a major part of your seborrheic dermatitis. It helps clear flakes and gives your scalp a fresh start.
How to naturally treat seborrheic dermatitis
Seborrheic dermatitis is a common skin problem. It mostly affects the scalp, but it can also show on the face, ears, eyebrows, chest, and around the nose. Many people use medicated shampoos, but some prefer natural ways to calm their skin.
Since seborrheic dermatitis is often linked to excess oil, yeast on the skin, stress, weak immunity, cold weather, and poor skin care, natural treatment focuses on calming the skin, reducing oil, controlling yeast, and keeping the skin barrier healthy.
Below are natural things commonly used for seborrheic dermatitis and how to use them:
1. Tea Tree Oil
Tea tree oil is one of the most popular natural remedies for seborrheic dermatitis. It has antifungal and antibacterial properties. This helps reduce the yeast that causes flakes and itching.
How to use:
Never apply pure tea tree oil directly to your skin. Mix 5–10 drops of tea tree oil into 2 tablespoons of a carrier oil like coconut oil or olive oil. Apply gently to the scalp or affected skin. Leave it on for 20–30 minutes, then wash off with a mild shampoo. You can do this 2 times a week.
2. Coconut Oil
Coconut oil helps moisturize dry skin and has mild antifungal effects. It also reduces itching and tightness caused by flakes.
How to use:
Warm a small amount of virgin coconut oil. Massage it gently into the scalp or affected area. Leave it on for 30 minutes or overnight if your skin is not too oily. Wash off with a gentle shampoo. Use 2–3 times a week. If coconut oil makes your flakes worse, stop using it.
3. Aloe Vera
Aloe vera is very calming for irritated skin. It reduces redness, itching, and inflammation. It also keeps the skin hydrated without making it greasy.
How to use:
Use fresh aloe vera gel or pure aloe gel with no alcohol. Apply a thin layer to the affected area. Leave it on for 20–30 minutes, then rinse with water. You can use aloe vera once daily, even on the face.
4. Apple Cider Vinegar
Apple cider vinegar helps balance skin pH and may reduce yeast growth. It also helps loosen flakes.
How to use:
Mix equal parts apple cider vinegar and water. Apply gently to the scalp using cotton or your fingers. Leave it on for 5–10 minutes, then rinse well. Do not use on broken or cracked skin. Use once a week only.
5. Honey (Raw Honey)
Raw honey has antifungal and soothing properties. It helps reduce redness and scaling.
How to use:
Mix 1 tablespoon of raw honey with a little warm water to thin it. Apply to the affected skin. Leave it on for 20 minutes, then rinse gently. You can do this 2–3 times a week.
6. Olive Oil
Olive oil helps soften hard flakes so they can be removed easily. It also moisturizes the skin.
How to use:
Massage a small amount of olive oil onto the scalp or flaky skin. Leave it on for 30 minutes. Gently loosen flakes with your fingers or a soft brush. Wash off with a mild shampoo. Do not leave it on too long, as oil can feed yeast if overused.
7. Oatmeal
Oatmeal is soothing and reduces itching. It is good for sensitive skin.
How to use:
Mix ground oatmeal with warm water to form a paste. Apply to affected areas and leave for 15–20 minutes. Rinse gently. This works well for face and body areas.
8. Proper Scalp and Skin Hygiene
Keeping the skin clean helps control oil and yeast buildup.
How to use:
Wash your scalp regularly with a gentle shampoo. Avoid harsh soaps on the face. Clean affected areas daily, but do not scrub hard. Pat skin dry instead of rubbing.
9. Diet Changes
What you eat can affect your skin. Some foods increase inflammation and oil production.
How to use:
Eat more fruits, vegetables, whole grains, and healthy fats like fish oil. Reduce sugar, alcohol, and highly processed foods. Drink enough water daily to keep skin hydrated from inside.
10. Stress Control
Stress is a common trigger for seborrheic dermatitis flare-ups.
How to use:
Practice deep breathing, light exercise, prayer, meditation, or walking. Get enough sleep. Managing stress helps reduce flare-ups naturally.
Important Tips
Natural treatments work slowly. You need patience and consistency. Always do a small patch test before trying any new remedy. If irritation gets worse, stop immediately. Natural care works best for mild to moderate seborrheic dermatitis. Severe cases may still need medical treatment.